What is a prime motivator of human activity? Desire.
Think: our hungers and desires motivate much of what we do. Even the desires we consider benign. Our desires drive and lead us to goals and destinations, our hungers motivate us to march to our goals, and would you guess how progress is possible?
Progress is motivated by a hunger that can never be quenched, it’s motivated by the simple tick of wanting to do or make something new, because humans can never be satisfied forever.
Without desire, what reason do we have to do anything? What reason do we have to pursue? What would motivate us to fight? What would motivate us to rise? Without desire, we’d just be a go-with-the-flow type species that does not want, and thus does not progress, because progess is based on want, for better or worse.